While security concerns have assumed salience across the globe, Afghanistan’s proximity to Central Asia has meant that security or perceptions of insecurity dominate the strategic discourse in the region. Issues that stand out include the challenges that the Central Asian states will face in terms of stability, ethnic tensions, radicalization of youth, destabilization of commodity flows and energy security and the impact that these could have on Central Asian society. However, security cannot just be defined in terms of security at the borders. It needs to be defined in ‘cosmopolitan’ terms through an array of issues like movements across borders, radicalism within states, the sharing of water, and various multilateral attempts at combating insecurity. This volume is an attempt to focus on some of these issues that reflect on perceptions of security principally from Indian and Uzbek positions. It examines shifts over the last two decades, from debates on the geopolitical importance of the region from a great game perspective to the salience of new engagements within the international arena.